Thyroid 24 Hour Urine Loading Analysis
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If the body is exposed to excess bromide, it can result in the bromide interfering with Iodine utilization in the body and creating a state of iodine deficiency. While your body has receptors for and needs iodine to make thyroid hormone, there is no known physiologic use for bromide in the body. When bromide binds to the iodine receptors in the thyroid gland, it disrupts the normal physiologic functioning of that gland. The body is very slow at eliminating bromide. The normal half-life of Bromide is 12 days and in cases of salt restriction and chronic bromide exposure, the half-life of Bromide can be as high as 40-50 days.
People who ingest bromide may feel dull and apathetic and have difficulty concentrating. Bromide also causes depression, headaches and irritability. When iodine is deficient, the toxicity of bromide is accelerated. Bromide toxicity may develop when bromide, acquired through environmental or dietary exposure causes bromide levels in the body to rise high enough to inhibit iodine utilization. Iodine supplementation will increase bromide excretion thereby reducing bromide toxicity.
Possible Sources of Bromide:
- Antibacterial agent for pools and hot tubs
- Brominated flour used as an anti-caking agent in the bread making process this includes pasta and cereal
- Brominated vegetable oil that may be added to citrus-flavored drinks (including Mountain Dew, AMP Energy drink, and some Gatorade products)
- Fire retardants (polybrominated diphenyl ether) added to many common household items (mattresses, carpeting, furniture foam, plastics of computers, televisions, radios, clothing, draperies, etc.)
- Fumigants used for termites and other pests
- Plastic products
- Prescription drugs, including Atrovent inhaler, Atrovent nasal spray, Ipratropium nasal spray, Pro-Panthine, Pyridostigmine bromide, and the Spiriva HandiHaler.
- Some fabric dyes
- Some personal care products
Symptoms of Bromide Toxicity: